Breaking News, Biophysics Blurb 18 Sep 2025 “New” ion channels in the nervous system – delta-type glutamate receptors! For decades, scientists have puzzled over the delta glutamate receptors (GluDs), mysterious proteins in the brain that are vital for… Edward Twomey
Breaking News, Biophysics Blurb 22 Apr 2025 How Brain Temperature Modulates Ion Channel Activity We found that the principal neurotransmitter receptors in the brain are more active at healthy/phyisological brain temperature (37 ˚C) and… Edward Twomey
Breaking News, Biophysics Blurb 24 Jul 2024 An expanded role for how the FDA-approved drug memantine functions. With the Jayaraman Lab at UT Health Houston, we show that memantine inhibits calcium-permeable AMPA receptors (CP-AMPARs). This is significant because… pendari1090
Breaking News, Biophysics Blurb 28 Nov 2023 How to tune neurotransmitter function Regulatory subunits tightly control the function of glutamate receptors, which enables our brains to tune responses to the neurotransmitter glutamate.… pendari1090
Breaking News, Biophysics Blurb 28 Nov 2023 Allosteric Competition and Inhibition! Small molecule therapeutics alter the three-dimensional landscape of glutamate receptors to control neurotransmission in disease states. We outline how therapeutic… pendari1090
Biophysics Blurb 16 Sep 2023 Why Time-Resolved Cryo-EM? Investigating the three-dimensional (3D) shapes of molecules such as proteins and nucleic acids enables us to understand their biological… pendari1090
