Investigating the three-dimensional (3D) shapes of molecules such as proteins and nucleic acids enables us to understand their biological... Read More






Investigating the three-dimensional (3D) shapes of molecules such as proteins and nucleic acids enables us to understand their biological... Read More
Our work on a new approach to time-resolved cryo-EM. Great work Alejandra and Calli! Link to BioRxiv!... Read More
Congrats to Lucas for passing his PMB GBO! ... Read More
The lab went to top golf! Ed definitely won. ... Read More
Twomey, E.C.*, Ji, Z.*, Wales, T.E., Bodnar, N.O., Ficarro, S.B., Marto, J.A., Engen, J.R., Rapoport, T.A. “Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding.” Science, Aug 2;365(6452). pii: eaax1033. PMID: 31249135.
Twomey, E.C., Yelshanskaya, M.V., Vassilevski, A.A., Sobolevsky, A.I. “Mechanisms of channel block in calcium-permeable AMPA receptors.” Neuron, 99: 956-968 (2018). PMID: 30122377. Featured as issue cover.
Twomey, E.C., Yelshanskaya, M.V., Grassucci, R.A., Frank, J., Sobolevsky, A.I. “Channel opening and gating mechanism in AMPA-subtype glutamate receptors.” Nature, 549: 60-65 (2017). PMID: 28737760.
Twomey, E.C., Yelshanskaya, M.V., Grassucci, R.A., Frank, J., Sobolevsky, A.I. “Elucidation of AMPA receptor-stargazin complexes by cryo-electron microscopy.” Science, 353: 83-86 (2016). PMID: 27365450.