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Browsing Category "Breaking News"

Congrats, Calli!

Congrats, Calli!

Calli Bonin, a star undergraduate in the lab, graduates from Hopkins! Congratulations, Calli!
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First publication!

Our time-resolved cryo-EM platform, C-SPAM, has been published in IUCrJ! Congratulations, Alejandra and Calli!┬áLink.    
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How to tune neurotransmitter function

Regulatory subunits tightly control the function of glutamate receptors, which enables our brains to tune responses to the neurotransmitter glutamate. The structural features of how this occurs were unknown, which is a major barrier in understanding brain function as well […]
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Allosteric Competition and Inhibition!

Small molecule therapeutics alter the three-dimensional landscape of glutamate receptors to control neurotransmission in disease states. We outline how therapeutic candidates inhibit glutamate receptors, and also observe a new phenomenon called allosteric competition, where two small molecules compete to control […]
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Why Time-Resolved Cryo-EM?

  Investigating the three-dimensional (3D) shapes of molecules such as proteins and nucleic acids enables us to understand their biological function, how therapeutic drugs interact with their targets, and how mutations may give rise to disease. A technology called cryo-electron […]
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First preprint!

Our work on a new approach to time-resolved cryo-EM. Great work Alejandra and Calli!   Link to BioRxiv!
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Lucas passed his GBO! Congrats, Lucas!

Congrats to Lucas for passing his PMB GBO!  
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The lab goes to Top Golf!

  The lab went to top golf! Ed definitely won.    
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Summer kayaking and paddle boarding!

    We had a lab outing out on Dundee Creek by Marshy Point!
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Lucas joins the lab for his PhD!

Lucas Dillard joined the lab from the PMB program!
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